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AIEDU
2005
185views more  AIEDU 2005»
14 years 9 months ago
A Bayesian Student Model without Hidden Nodes and its Comparison with Item Response Theory
The Bayesian framework offers a number of techniques for inferring an individual's knowledge state from evidence of mastery of concepts or skills. A typical application where ...
Michel C. Desmarais, Xiaoming Pu
CIKM
2008
Springer
14 years 11 months ago
Passage relevance models for genomics search
We present a passage relevance model for integrating syntactic and semantic evidence of biomedical concepts and topics using a probabilistic graphical model. Component models of t...
Jay Urbain, Ophir Frieder, Nazli Goharian
BMCBI
2008
87views more  BMCBI 2008»
14 years 10 months ago
Protein structure search and local structure characterization
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
Shih-Yen Ku, Yuh-Jyh Hu
BMCBI
2006
149views more  BMCBI 2006»
14 years 9 months ago
REtools: A laboratory program for restriction enzyme work: enzyme selection and reaction condition assistance
Background: Restriction enzymes are one of the everyday tools used in molecular biology. The continuously expanding panel of known restriction enzymes (several thousands) renders ...
Patrick Martin, Kim E. Boulukos, Philippe Pognonec
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu