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BMCBI
2008
133views more  BMCBI 2008»
14 years 9 months ago
MS-DOCK: Accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Background: The number of protein targets with a known or predicted tri-dimensional structure and of drug-like chemical compounds is growing rapidly and so is the need for new the...
Nicolas Sauton, David Lagorce, Bruno O. Villoutrei...
BMCBI
2007
139views more  BMCBI 2007»
14 years 9 months ago
XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
Aaron M. Newman, James B. Cooper
FSS
2008
130views more  FSS 2008»
14 years 9 months ago
A fuzzy k-partitions model for categorical data and its comparison to the GoM model
The grade of membership (GoM) model uses fuzzy sets as memberships of each individual to extreme profiles (or classes) on the likelihood function of multivariate multinomial distr...
Miin-Shen Yang, Yu-Hsuan Chiang, Chiu-Chi Chen, Ch...
BMCBI
2006
82views more  BMCBI 2006»
14 years 9 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...
BMCBI
2006
124views more  BMCBI 2006»
14 years 9 months ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...