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WG
2005
Springer
15 years 5 months ago
Fixed-Parameter Algorithms for Protein Similarity Search Under mRNA Structure Constraints
Abstract. In the context of protein engineering, we consider the problem of computing an mRNA sequence of maximal codon-wise similarity to a given mRNA (and consequently, to a give...
Guillaume Blin, Guillaume Fertin, Danny Hermelin, ...
BMCBI
2010
129views more  BMCBI 2010»
14 years 12 months ago
The LabelHash Algorithm for Substructure Matching
Background: There is an increasing number of proteins with known structure but unknown function. Determining their function would have a significant impact on understanding diseas...
Mark Moll, Drew H. Bryant, Lydia E. Kavraki
ISBRA
2007
Springer
15 years 6 months ago
Clustering Algorithms Optimizer: A Framework for Large Datasets
Clustering algorithms are employed in many bioinformatics tasks, including categorization of protein sequences and analysis of gene-expression data. Although these algorithms are r...
Roy Varshavsky, David Horn, Michal Linial
GECCO
2006
Springer
159views Optimization» more  GECCO 2006»
15 years 3 months ago
Identification of weak motifs in multiple biological sequences using genetic algorithm
Recognition of motifs in multiple unaligned sequences provides an insight into protein structure and function. The task of discovering these motifs is very challenging because mos...
Topon Kumar Paul, Hitoshi Iba
BMCBI
2006
102views more  BMCBI 2006»
14 years 12 months ago
Protein secondary structure prediction for a single-sequence using hidden semi-Markov models
Background: The accuracy of protein secondary structure prediction has been improving steadily towards the 88% estimated theoretical limit. There are two types of prediction algor...
Zafer Aydin, Yucel Altunbasak, Mark Borodovsky