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COMPLIFE
2006
Springer
15 years 1 months ago
A New Approach to Flux Coupling Analysis of Metabolic Networks
Flux coupling analysis is a method to identify blocked and coupled reactions in a metabolic network at steady state. We present a new approach to flux coupling analysis, which uses...
Abdelhalim Larhlimi, Alexander Bockmayr
BMCBI
2011
14 years 1 months ago
FFCA: a feasibility-based method for flux coupling analysis of metabolic networks
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...
László Dávid, Sayed-Amir Mara...
BMCBI
2007
97views more  BMCBI 2007»
14 years 10 months ago
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Background: An indirect approach is usually used to estimate the metabolic fluxes of an organism: couple the available measurements with known biological constraints (e.g. stoichi...
Francisco Llaneras, Jesús Picó
BMCBI
2010
133views more  BMCBI 2010»
14 years 10 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
BMCBI
2004
154views more  BMCBI 2004»
14 years 10 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt