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» A New Approach to Protein Identification
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BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
BILDMED
2008
124views Algorithms» more  BILDMED 2008»
14 years 11 months ago
Geometric Alignment of 2D Gel Electrophoresis Images
Abstract. A key technique for protein analysis is the geometric alignment of 2D gel electrophoresis (2-DE) images. We introduce a new hybrid elastic registration approach for 2-DE ...
Stefan Wörz, Marie-Luise Winz, Karl Rohr
CSB
2005
IEEE
129views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Rule Clustering and Super-rule Generation for Transmembrane Segments Prediction
The explanation of a decision is important for the acceptance of machine learning technology in bioinformatics applications such as protein structure prediction. In past research,...
Jieyue He, Bernard Chen, Hae-Jin Hu, Robert W. Har...
BMCBI
2008
87views more  BMCBI 2008»
14 years 10 months ago
Volume-based solvation models out-perform area-based models in combined studies of wild-type and mutated protein-protein interfa
Background: Empirical binding models have previously been investigated for the energetics of protein complexation (G models) and for the influence of mutations on complexation (i....
Salim Bougouffa, Jim Warwicker
JCC
2011
109views more  JCC 2011»
14 years 26 days ago
VoteDock: Consensus docking method for prediction of protein-ligand interactions
: Molecular recognition plays a fundamental role in all biological processes, and that is why great efforts have been made to understand and predict protein–ligand interactions. ...
Dariusz Plewczynski, Michal Lazniewski, Marcin von...