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» A New Approach to Protein Identification
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BMCBI
2010
125views more  BMCBI 2010»
14 years 10 months ago
A computational screen for site selective A-to-I editing detects novel sites in neuron specific Hu proteins
Background: Several bioinformatic approaches have previously been used to find novel sites of ADAR mediated A-to-I RNA editing in human. These studies have discovered thousands of...
Mats Ensterö, Örjan Åkerborg, Dani...
BMCBI
2006
159views more  BMCBI 2006»
14 years 9 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
BMCBI
2011
14 years 4 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
ALGORITHMICA
1999
84views more  ALGORITHMICA 1999»
14 years 9 months ago
Computational Approaches to Drug Design
Abstract. The rational approach to pharmaceutical drug design begins with an investigation of the relationship between chemical structure and biological activity. Information gaine...
Paul W. Finn, Lydia E. Kavraki
TCBB
2008
102views more  TCBB 2008»
14 years 9 months ago
Identification of Protein Coding Regions Using the Modified Gabor-Wavelet Transform
An important topic in genomic sequence analysis is the identification of protein coding regions. In this context, several coding DNA model-independent methods based on the occurren...
Jesus P. Mena-Chalco, Helaine Carrer, Yossi Zana, ...