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» A New Approach to Protein Identification
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GCB
2005
Springer
117views Biometrics» more  GCB 2005»
15 years 7 months ago
Generation of 3D templates of active sites of proteins with rigid prosthetic groups
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
Jean-Christophe Nebel
BMCBI
2008
87views more  BMCBI 2008»
15 years 2 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
BMCBI
2010
176views more  BMCBI 2010»
15 years 2 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
BIB
2011
14 years 9 months ago
Protein mass spectra data analysis for clinical biomarker discovery: a global review
The identification of new diagnostic or prognostic biomarkers is one of the main aims of clinical cancer research. In recent years there has been a growing interest in using high ...
Pascal Roy, Caroline Truntzer, Delphine Maucort-Bo...
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
15 years 5 months ago
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Christopher James Langmead, Bruce Randall Donald