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» A New Approach to Protein Identification
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CIBCB
2009
IEEE
14 years 11 months ago
An application of the metric access methods to the mass spectrometry data
Mass spectrometry is a very popular method for protein and peptide identification nowadays. Abundance of data generated in this way grows exponentially every year and although ther...
Jiri Novák, David Hoksza
RECOMB
2005
Springer
15 years 10 months ago
Predicting Transcription Factor Binding Sites Using Structural Knowledge
Abstract. Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structu...
Tommy Kaplan, Nir Friedman, Hanah Margalit
BMCBI
2010
154views more  BMCBI 2010»
14 years 10 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2007
93views more  BMCBI 2007»
14 years 9 months ago
SVM-Fold: a tool for discriminative multi-class protein fold and superfamily recognition
Background: Predicting a protein’s structural class from its amino acid sequence is a fundamental problem in computational biology. Much recent work has focused on developing ne...
Iain Melvin, Eugene Ie, Rui Kuang, Jason Weston, W...
BMCBI
2007
134views more  BMCBI 2007»
14 years 10 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...