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» A New Approach to Protein Identification
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BMCBI
2008
108views more  BMCBI 2008»
14 years 10 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
14 years 9 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
MLMTA
2007
14 years 11 months ago
Prediction of Protein Secondary Structures with a Novel Kernel Density Estimator
- Though prediction of protein secondary structures has been an active research issue in bioinformatics for quite a few years and many approaches have been proposed, a new challeng...
Yen-Jen Oyang, Darby Tien-Hao Chang, Yu-Yen Ou, Ha...
DAGSTUHL
2009
14 years 11 months ago
Learning Highly Structured Manifolds: Harnessing the Power of SOMs
Abstract. In this paper we elaborate on the challenges of learning manifolds that have many relevant clusters, and where the clusters can have widely varying statistics. We call su...
Erzsébet Merényi, Kadim Tasdemir, Li...
BMCBI
2008
94views more  BMCBI 2008»
14 years 10 months ago
Conserved co-expression for candidate disease gene prioritization
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
Martin Oti, Jeroen van Reeuwijk, Martijn A. Huynen...