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» A New Approach to Protein Identification
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BMCBI
2005
104views more  BMCBI 2005»
14 years 9 months ago
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer i
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
Federica Cavallo, Annalisa Astolfi, Manuela Iezzi,...
ISMIS
2005
Springer
15 years 3 months ago
A Machine Text-Inspired Machine Learning Approach for Identification of Transmembrane Helix Boundaries
In this paper, we adapt a statistical learning approach, inspired by automated topic segmentation techniques in speech-recognized documents to the challenging protein segmentation ...
Betty Yee Man Cheng, Jaime G. Carbonell, Judith Kl...
IMSCCS
2006
IEEE
15 years 3 months ago
Identification of New Members of Hydrophobin Family Using Primary Structure Analysis
Background: Hydrophobins are fungal proteins that can turn into amphipathic membranes at hydrophilic/hydrophobic interfaces by self-assembly. The assemblages by Class I hydrophobi...
Kuan Yang, Youping Deng, Chaoyang Zhang, Mohamed O...
RECOMB
2008
Springer
15 years 10 months ago
A Bayesian Approach to Protein Inference Problem in Shotgun Proteomics
The protein inference problem represents a major challenge in shotgun proteomics. Here we describe a novel Bayesian approach to address this challenge that incorporates the predict...
Yong Fuga Li, Randy J. Arnold, Yixue Li, Predrag R...
BMCBI
2007
102views more  BMCBI 2007»
14 years 9 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein