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» A New Approach to Protein Identification
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LION
2009
Springer
114views Optimization» more  LION 2009»
15 years 4 months ago
Substitution Matrices and Mutual Information Approaches to Modeling Evolution
Abstract. Substitution matrices are at the heart of Bioinformatics: sequence alignment, database search, phylogenetic inference, protein family classication are based on Blosum, P...
Stephan Kitchovitch, Yuedong Song, Richard C. van ...
PAKDD
2004
ACM
131views Data Mining» more  PAKDD 2004»
15 years 3 months ago
A Tree-Based Approach to the Discovery of Diagnostic Biomarkers for Ovarian Cancer
Computational diagnosis of cancer is a classification problem, and it has two special requirements on a learning algorithm: perfect accuracy and small number of features used in t...
Jinyan Li, Kotagiri Ramamohanarao
TSMC
2010
14 years 4 months ago
On Robust Stability of Stochastic Genetic Regulatory Networks With Time Delays: A Delay Fractioning Approach
Robust stability serves as an important regulation mechanism in system biology and synthetic biology. In this paper, the robust stability analysis problem is investigated for a cla...
Yao Wang, Zidong Wang, Jinling Liang
BMCBI
2006
143views more  BMCBI 2006»
14 years 10 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
BMCBI
2006
114views more  BMCBI 2006»
14 years 10 months ago
A high level interface to SCOP and ASTRAL implemented in Python
Background: Benchmarking algorithms in structural bioinformatics often involves the construction of datasets of proteins with given sequence and structural properties. The SCOP da...
James A. Casbon, Gavin E. Crooks, Mansoor A. S. Sa...