Protein phosphorylation is a crucial regulatory mechanism in various organisms. With recent improvements in mass spectrometry, phosphorylation site data are rapidly accumulating. D...
Jianjiong Gao, Ganesh Kumar Agrawal, Jay J. Thelen...
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...
In this study, we propose a new machine learning model namely, Adaptive Locality-Effective Kernel Machine (Adaptive-LEKM) for protein phosphorylation site prediction. Adaptive-LEK...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
Neil F. W. Saunders, Ross I. Brinkworth, Thomas Hu...