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    » A Parameterized Algorithm for Protein Structure Alignment
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    BMCBI
    2005
    119views more  BMCBI 2005»
    The distance-profile representation and its application to detection of distantly related protein families
    14 years 11 months ago
    The distance-profile representation and its application to detection of distantly related protein families
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    Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
    Chin-Jen Ku, Golan Yona
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    BMCBI
    2005
    198views more  BMCBI 2005»
    Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
    14 years 11 months ago
    Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
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    Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
    Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
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    105
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    BMCBI
    2004
    208views more  BMCBI 2004»
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
    14 years 11 months ago
    Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
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    Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
    Vadim Alexandrov, Mark Gerstein
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    BIBE
    2007
    IEEE
    128views Bioinformatics» more  BIBE 2007»
    QOMA2: Optimizing the alignment of many sequences
    15 years 6 months ago
    QOMA2: Optimizing the alignment of many sequences
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    Abstract—We consider the problem of aligning multiple protein sequences with the goal of maximizing the SP (Sum-of-Pairs) score, when the number of sequences is large. The QOMA (...
    Xu Zhang, Tamer Kahveci
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    103
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    BMCBI
    2005
    115views more  BMCBI 2005»
    Statistical distributions of optimal global alignment scores of random protein sequences
    14 years 11 months ago
    Statistical distributions of optimal global alignment scores of random protein sequences
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    Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
    Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
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