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» A Parameterized Algorithm for Protein Structure Alignment
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97
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WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
15 years 5 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
CAIP
2009
Springer
155views Image Analysis» more  CAIP 2009»
15 years 6 months ago
Algorithms for the Sample Mean of Graphs
Measures of central tendency for graphs are important for protoype construction, frequent substructure mining, and multiple alignment of protein structures. This contribution propo...
Brijnesh J. Jain, Klaus Obermayer
100
Voted
BMCBI
2005
162views more  BMCBI 2005»
14 years 11 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
77
Voted
BMCBI
2008
176views more  BMCBI 2008»
14 years 11 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
107
Voted
JCB
2000
101views more  JCB 2000»
14 years 11 months ago
Evaluation Measures of Multiple Sequence Alignments
Multiple sequence alignments (MSAs) are frequently used in the study of families of protein sequences or DNA/RNA sequences. They are a fundamental tool for the understanding of th...
Gaston H. Gonnet, Chantal Korostensky, Steven A. B...