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» A Parameterized Algorithm for Protein Structure Alignment
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CLEF
2009
Springer
13 years 7 months ago
Morphological Analysis by Multiple Sequence Alignment
In biological sequence processing, Multiple Sequence Alignment (MSA) techniques capture information about long-distance dependencies and the three-dimensional structure of protein ...
Tzvetan Tchoukalov, Christian Monson, Brian Roark
BMCBI
2002
133views more  BMCBI 2002»
13 years 6 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
GCCB
2006
13 years 10 months ago
Accelerated microRNA-Precursor Detection Using the Smith-Waterman Algorithm on FPGAs
During the last few years more and more functionalities of RNA have been discovered that were previously thought of being carried out by proteins alone. One of the most striking di...
Patrick May, Gunnar W. Klau, Markus Bauer, Thomas ...
BMCBI
2010
121views more  BMCBI 2010»
13 years 6 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
BMCBI
2008
164views more  BMCBI 2008»
13 years 6 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke