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BMCBI
2010
103views more  BMCBI 2010»
15 years 6 months ago
A method of predicting changes in human gene splicing induced by genetic variants in context of cis-acting elements
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...
Alexander G. Churbanov, Igor Vorechovsky, Chindo H...
BMCBI
2008
135views more  BMCBI 2008»
15 years 6 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2010
110views more  BMCBI 2010»
15 years 5 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
IJIT
2004
15 years 7 months ago
An Improved Preprocessing for Biosonar Target Classification
An improved processing description to be employed in biosonar signal processing in a cochlea model is proposed and examined. It is compared to conventional models using a modified ...
Turgay Temel, John Hallam
DEBS
2010
ACM
15 years 9 months ago
Workload characterization for operator-based distributed stream processing applications
Operator-based programming languages provide an effective development model for large scale stream processing applications. A stream processing application consists of many runtim...
Xiaolan J. Zhang, Sujay Parekh, Bugra Gedik, Henri...