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BMCBI
2007
95views more  BMCBI 2007»
15 years 6 months ago
Phylogenetic tree information aids supervised learning for predicting protein-protein interaction based on distance matrices
Background: Protein-protein interactions are critical for cellular functions. Recently developed computational approaches for predicting protein-protein interactions utilize co-ev...
Roger A. Craig, Li Liao
165
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BMCBI
2010
147views more  BMCBI 2010»
15 years 6 months ago
baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data
Background: High throughput sequencing has become an important technology for studying expression levels in many types of genomic, and particularly transcriptomic, data. One key w...
Thomas J. Hardcastle, Krystyna A. Kelly
185
Voted
BMCBI
2007
139views more  BMCBI 2007»
15 years 6 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
BMCBI
2010
87views more  BMCBI 2010»
15 years 6 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
A method for automatically extracting infectious disease-related primers and probes from the literature
Background: Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the ...
Miguel García-Remesal, Alejandro Cuevas, Vi...