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» A Permutation Approach to Validation
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BMCBI
2006
78views more  BMCBI 2006»
15 years 6 months ago
Subfamily logos: visualization of sequence deviations at alignment positions with high information content
Background: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserve...
Eric Beitz
BMCBI
2006
205views more  BMCBI 2006»
15 years 6 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
BMCBI
2006
140views more  BMCBI 2006»
15 years 6 months ago
Feature selection using Haar wavelet power spectrum
Background: Feature selection is an approach to overcome the 'curse of dimensionality' in complex researches like disease classification using microarrays. Statistical m...
Prabakaran Subramani, Rajendra Sahu, Shekhar Verma
155
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BMCBI
2006
87views more  BMCBI 2006»
15 years 6 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
205
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BMCBI
2006
128views more  BMCBI 2006»
15 years 6 months ago
Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...