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» A Perspective on Evolutionary Computation
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BMCBI
2010
156views more  BMCBI 2010»
14 years 12 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
BMCBI
2008
175views more  BMCBI 2008»
14 years 12 months ago
Comprehensive inventory of protein complexes in the Protein Data Bank from consistent classification of interfaces
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...
Andrew J. Bordner, Andrey A. Gorin
BMCBI
2007
126views more  BMCBI 2007»
14 years 12 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2008
178views more  BMCBI 2008»
14 years 12 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2008
107views more  BMCBI 2008»
14 years 12 months ago
Extended Newick: it is time for a standard representation of phylogenetic networks
Background: Phylogenetic trees resulting from molecular phylogenetic analysis are available in Newick format from specialized databases but when it comes to phylogenetic networks,...
Gabriel Cardona, Francesc Rosselló, Gabriel...