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109
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ALMOB
2008
127views more  ALMOB 2008»
15 years 21 days ago
HuMiTar: A sequence-based method for prediction of human microRNA targets
Background: MicroRNAs (miRs) are small noncoding RNAs that bind to complementary/partially complementary sites in the 3' untranslated regions of target genes to regulate prot...
Jishou Ruan, Hanzhe Chen, Lukasz A. Kurgan, Ke Che...
98
Voted
BMCBI
2010
119views more  BMCBI 2010»
15 years 20 days ago
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
Qi Liu, Qian Xu, Vincent Wenchen Zheng, Hong Xue, ...
106
Voted
BMCBI
2010
165views more  BMCBI 2010»
15 years 20 days ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
BMCBI
2006
89views more  BMCBI 2006»
15 years 18 days ago
SPODOBASE : an EST database for the lepidopteran crop pest Spodoptera
Background: The Lepidoptera Spodoptera frugiperda is a pest which causes widespread economic damage on a variety of crop plants. It is also well known through its famous Sf9 cell ...
Vincent Nègre, Thierry Hotelier, Anne-Natha...
BMCBI
2007
148views more  BMCBI 2007»
15 years 17 days ago
p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data
Background: The p53 gene family consists of the three genes p53, p63 and p73, which have polyhedral non-overlapping functions in pivotal cellular processes such as DNA synthesis a...
Elisabetta Sbisà, Domenico Catalano, Giorgi...