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» A Prototype for Multiple Whole Genome Alignment
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BMCBI
2008
99views more  BMCBI 2008»
13 years 6 months ago
Multiple organism algorithm for finding ultraconserved elements
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
Scott Christley, Neil F. Lobo, Gregory R. Madey
BMCBI
2011
13 years 1 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...
BMCBI
2006
122views more  BMCBI 2006»
13 years 6 months ago
CoSMoS: Conserved Sequence Motif Search in the proteome
Background: With the ever-increasing number of gene sequences in the public databases, generating and analyzing multiple sequence alignments becomes increasingly time consuming. N...
Xiao I. Liu, Neeraj Korde, Ursula Jakob, Lars I. L...
JCB
2008
122views more  JCB 2008»
13 years 6 months ago
Space Efficient Computation of Rare Maximal Exact Matches between Multiple Sequences
In this article, we propose a new method for computing rare maximal exact matches between multiple sequences. A rare match between k sequences S1; : : :; Sk is a string that occur...
Enno Ohlebusch, Stefan Kurtz
BMCBI
2010
160views more  BMCBI 2010»
13 years 1 months ago
eHive: An Artificial Intelligence workflow system for genomic analysis
Background: The Ensembl project produces updates to its comparative genomics resources with each of its several releases per year. During each release cycle approximately two week...
Jessica Severin, Kathryn Beal, Albert J. Vilella, ...