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» A Reconfigurable Computing Model for Biological Research
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ARC
2009
Springer
175views Hardware» more  ARC 2009»
15 years 6 months ago
A Hardware Accelerated Simulation Environment for Spiking Neural Networks
Spiking Neural Networks (SNNs) model the biological functions of the human brain enabling neuro/computer scientists to investigate how arrays of neurons can be used to solve comput...
Brendan P. Glackin, Jim Harkin, T. Martin McGinnit...
DATE
2005
IEEE
152views Hardware» more  DATE 2005»
15 years 5 months ago
Design of Fault-Tolerant and Dynamically-Reconfigurable Microfluidic Biochips
Technology Roadmap for Semiconductors (ITRS) clearly identifies the integration of electrochemical and electrobiological techniques as one of the system-level design challenges tha...
Fei Su, Krishnendu Chakrabarty
BMCBI
2006
194views more  BMCBI 2006»
14 years 11 months ago
Novel metaheuristic for parameter estimation in nonlinear dynamic biological systems
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
Maria Rodriguez-Fernandez, Jose A. Egea, Julio R. ...
BMCBI
2006
123views more  BMCBI 2006»
14 years 11 months ago
SBEAMS-Microarray: database software supporting genomic expression analyses for systems biology
Background: The biological information in genomic expression data can be understood, and computationally extracted, in the context of systems of interacting molecules. The automat...
Bruz Marzolf, Eric W. Deutsch, Patrick Moss, David...
RECOMB
2005
Springer
16 years 1 days ago
Comparative Systems Biology of the Sporulation Initiation Network in Prokaryotes
Many years of experimental and computational molecular biology of model organisms such as Escherichia coli and Saccharomyces cerevisiae has elucidated the gene regulatory network i...
Michiel J. L. de Hoon, Dennis Vitkup