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BMCBI
2008
133views more  BMCBI 2008»
14 years 10 months ago
SPIKE - a database, visualization and analysis tool of cellular signaling pathways
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
Ran Elkon, Rita Vesterman, Nira Amit, Igor Ulitsky...
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
BMCBI
2007
124views more  BMCBI 2007»
14 years 10 months ago
Analysis on multi-domain cooperation for predicting protein-protein interactions
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Rui-Sheng Wang, Yong Wang, Ling-Yun Wu, Xiang-Sun ...
BMCBI
2008
114views more  BMCBI 2008»
14 years 10 months ago
A visual analytics approach for understanding biclustering results from microarray data
Background: Microarray analysis is an important area of bioinformatics. In the last few years, biclustering has become one of the most popular methods for classifying data from mi...
Rodrigo Santamaría, Roberto Therón, ...
BMCBI
2010
142views more  BMCBI 2010»
14 years 10 months ago
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background: Likelihood-based phylogenetic inference is generally considered to be the most reliable classification method for unknown sequences. However, traditional likelihood-ba...
Frederick A. Matsen III, Robin B. Kodner, E. Virgi...
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