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BMCBI
2005
93views more  BMCBI 2005»
15 years 5 months ago
SPdb - a signal peptide database
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...
Khar Heng Choo, Tin Wee Tan, Shoba Ranganathan
TIT
2008
116views more  TIT 2008»
15 years 5 months ago
On the Complexity of Hardness Amplification
We study the task of transforming a hard function f, with which any small circuit disagrees on (1 - )/2 fraction of the input, into a harder function f , with which any small circ...
Chi-Jen Lu, Shi-Chun Tsai, Hsin-Lung Wu
BMCBI
2005
136views more  BMCBI 2005»
15 years 5 months ago
Automatic detection of false annotations via binary property clustering
Background: Computational protein annotation methods occasionally introduce errors. Falsepositive (FP) errors are annotations that are mistakenly associated with a protein. Such f...
Noam Kaplan, Michal Linial
BMCBI
2005
127views more  BMCBI 2005»
15 years 5 months ago
Dynamic modeling of cis-regulatory circuits and gene expression prediction via cross-gene identification
Background: Gene expression programs depend on recognition of cis elements in promoter region of target genes by transcription factors (TFs), but how TFs regulate gene expression ...
Li-Hsieh Lin, Hsiao-Ching Lee, Wen-Hsiung Li, Bor-...
BMCBI
2005
115views more  BMCBI 2005»
15 years 5 months ago
MPrime: efficient large scale multiple primer and oligonucleotide design for customized gene microarrays
Background: Enhancements in sequencing technology have recently yielded assemblies of large genomes including rat, mouse, human, fruit fly, and zebrafish. The availability of larg...
Eric C. Rouchka, Abdelnaby Khalyfa, Nigel G. F. Co...
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