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BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
15 years 2 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
CMIG
2010
110views more  CMIG 2010»
14 years 9 months ago
Unsupervised SVM-based gridding for DNA microarray images
This paper presents a novel method for unsupervised DNA microarray gridding based on Support Vector Machines (SVMs). Each spot is a small region on the microarray surface where cha...
Dimitris G. Bariamis, Dimitris Maroulis, Dimitrios...
BMCBI
2008
123views more  BMCBI 2008»
15 years 2 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
ALMOB
2008
160views more  ALMOB 2008»
15 years 2 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
COMPSEC
2004
131views more  COMPSEC 2004»
15 years 1 months ago
Biometric random number generators
Abstract Up to now biometric methods have been used in cryptography for authentication purposes. In this paper we propose to use biological data for generating sequences of random ...
Janusz Szczepanski, Elek Wajnryb, José M. A...