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» A Sensitive Sequence Comparison Method
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115
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BMCBI
2004
113views more  BMCBI 2004»
15 years 1 months ago
Influence of microarrays experiments missing values on the stability of gene groups by hierarchical clustering
Background: Microarray technologies produced large amount of data. The hierarchical clustering is commonly used to identify clusters of co-expressed genes. However, microarray dat...
Alexandre G. de Brevern, Serge A. Hazout, Alain Ma...
ALMOB
2008
95views more  ALMOB 2008»
15 years 2 months ago
A stitch in time: Efficient computation of genomic DNA melting bubbles
Background: It is of biological interest to make genome-wide predictions of the locations of DNA melting bubbles using statistical mechanics models. Computationally, this poses th...
Eivind Tøstesen
130
Voted
BMCBI
2010
160views more  BMCBI 2010»
15 years 2 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
121
Voted
BMCBI
2007
143views more  BMCBI 2007»
15 years 2 months ago
RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules
Background: In recent years, RNA molecules that are not translated into proteins (ncRNAs) have drawn a great deal of attention, as they were shown to be involved in many cellular ...
Yair Horesh, Tirza Doniger, Shulamit Michaeli, Ron...
101
Voted
BMCBI
2005
92views more  BMCBI 2005»
15 years 1 months ago
Predicting functional sites with an automated algorithm suitable for heterogeneous datasets
Background: In a previous report (La et al., Proteins, 2005), we have demonstrated that the identification of phylogenetic motifs, protein sequence fragments conserving the overal...
David La, Dennis R. Livesay