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» A Sensitive Sequence Comparison Method
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BMCBI
2008
165views more  BMCBI 2008»
14 years 9 months ago
Peak intensity prediction in MALDI-TOF mass spectrometry: A machine learning study to support quantitative proteomics
Background: Mass spectrometry is a key technique in proteomics and can be used to analyze complex samples quickly. One key problem with the mass spectrometric analysis of peptides...
Wiebke Timm, Alexandra Scherbart, Sebastian Bö...
BMCBI
2008
84views more  BMCBI 2008»
14 years 9 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....
89
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BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
Development and implementation of an algorithm for detection of protein complexes in large interaction networks
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
Md. Altaf-Ul-Amin, Yoko Shinbo, Kenji Mihara, Ken ...
FUIN
2006
98views more  FUIN 2006»
14 years 9 months ago
On-line Approximate String Matching in Natural Language
We consider approximate pattern matching in natural language text. We use the words of the text as the alphabet, instead of the characters as in traditional string matching approac...
Kimmo Fredriksson
86
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BMCBI
2005
145views more  BMCBI 2005»
14 years 9 months ago
CAGER: classification analysis of gene expression regulation using multiple information sources
Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
Jianhua Ruan, Weixiong Zhang