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» A Sensitive Sequence Comparison Method
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BIBE
2004
IEEE
15 years 5 months ago
Efficient Methods for Generating Optimal Single and Multiple Spaced Seeds
Biologists highly rely on good algorithms for finding homologous regions in bimolecular sequences. An advanced homology search program named PatternHunter has recently been develo...
I-Hsuan Yang, Sheng-Ho Wang, Yang-Ho Chen, Pao-Hsi...
BMCBI
2008
172views more  BMCBI 2008»
15 years 2 months ago
Compo: composite motif discovery using discrete models
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...
Geir Kjetil Sandve, Osman Abul, Finn Drablø...
BMCBI
2006
124views more  BMCBI 2006»
15 years 1 months ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...
BMCBI
2010
123views more  BMCBI 2010»
15 years 2 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
BMCBI
2007
106views more  BMCBI 2007»
15 years 1 months ago
Simultaneous identification of long similar substrings in large sets of sequences
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
Jürgen Kleffe, Friedrich Möller, Burghar...