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» A Sensitive Sequence Comparison Method
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AIME
1997
Springer
15 years 6 months ago
Detecting Very Early Stages of Dementia from Normal Aging with Machine Learning Methods
We used Machine Learning (ML) methods to learn the best decision rules to distinguish normal brain aging from the earliest stages of dementia using subsamples of 198 normal and 244...
William Rodman Shankle, Subramani Mani, Michael J....
BMCBI
2008
164views more  BMCBI 2008»
15 years 2 months ago
Word correlation matrices for protein sequence analysis and remote homology detection
Background: Classification of protein sequences is a central problem in computational biology. Currently, among computational methods discriminative kernel-based approaches provid...
Thomas Lingner, Peter Meinicke
109
Voted
BMCBI
2008
122views more  BMCBI 2008»
15 years 2 months ago
Determining gene expression on a single pair of microarrays
Background: In microarray experiments the numbers of replicates are often limited due to factors such as cost, availability of sample or poor hybridization. There are currently fe...
Robert W. Reid, Anthony A. Fodor
BMCBI
2010
111views more  BMCBI 2010»
15 years 2 months ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
BMCBI
2006
122views more  BMCBI 2006»
15 years 1 months ago
Genome comparison using Gene Ontology (GO) with statistical testing
Background: Automated comparison of complete sets of genes encoded in two genomes can provide insight on the genetic basis of differences in biological traits between species. Gen...
Zhaotao Cai, Xizeng Mao, Songgang Li, Liping Wei