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» A Sensitive Sequence Comparison Method
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BMCBI
2010
125views more  BMCBI 2010»
15 years 2 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
BMCBI
2007
128views more  BMCBI 2007»
15 years 2 months ago
Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
Oliviero Carugo
NN
2007
Springer
162views Neural Networks» more  NN 2007»
15 years 1 months ago
Learning grammatical structure with Echo State Networks
Echo State Networks (ESNs) have been shown to be effective for a number of tasks, including motor control, dynamic time series prediction, and memorizing musical sequences. Howeve...
Matthew H. Tong, Adam D. Bickett, Eric M. Christia...
BMCBI
2008
108views more  BMCBI 2008»
15 years 2 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BMCBI
2006
166views more  BMCBI 2006»
15 years 2 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...