653 search results - page 6 / 131 » A Sensitive Sequence Comparison Method |
BMCBI
2004
14 years 9 months ago
2004
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
ICASSP
2007
IEEE
15 years 3 months ago
2007
IEEE
Recently, profile context-sensitive HMMs (profile-csHMMs) have been proposed which are very effective in modeling the common patterns and motifs in related symbol sequences. Pro...
58
Voted
BMCBI
2007
14 years 9 months ago
2007
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
BMCBI
2005
14 years 9 months ago
2005
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
85
Voted
RECOMB
2004
Springer
15 years 9 months ago
2004
Springer
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...