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BMCBI
2010
139views more  BMCBI 2010»
15 years 3 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2007
165views more  BMCBI 2007»
15 years 3 months ago
Direct maximum parsimony phylogeny reconstruction from genotype data
Background: Maximum parsimony phylogenetic tree reconstruction from genetic variation data is a fundamental problem in computational genetics with many practical applications in p...
Srinath Sridhar, Fumei Lam, Guy E. Blelloch, R. Ra...
CSDA
2008
128views more  CSDA 2008»
15 years 3 months ago
Classification tree analysis using TARGET
Tree models are valuable tools for predictive modeling and data mining. Traditional tree-growing methodologies such as CART are known to suffer from problems including greediness,...
J. Brian Gray, Guangzhe Fan
EC
2008
116views ECommerce» more  EC 2008»
15 years 3 months ago
Efficient Evaluation Functions for Evolving Coordination
Abstract-- This paper presents a method for creating evaluation functions that efficiently promote coordination in a multiagent system, allowing single-agent evolutionary computati...
Adrian K. Agogino, Kagan Tumer
BMCBI
2006
122views more  BMCBI 2006»
15 years 3 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
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