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BMCBI
2010
2010
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
14 years 10 months ago
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
BMCBI
2008
14 years 10 months ago
2008
Background: Both microarrays and quantitative real-time PCR are convenient tools for studying the transcriptional levels of genes. The former is preferable for large scale studies...
BMCBI
2008
14 years 10 months ago
2008
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
BMCBI
2007
14 years 10 months ago
2007
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
BMCBI
2008
14 years 10 months ago
2008
Background: Structural alignment of RNAs is becoming important, since the discovery of functional non-coding RNAs (ncRNAs). Recent studies, mainly based on various approximations ...