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110
Voted
BMCBI
2010
15 years 17 days ago
2010
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
106
Voted
BMCBI
2008
15 years 17 days ago
2008
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
BMCBI
2008
15 years 17 days ago
2008
Background: The analysis of high-throughput gene expression data sets derived from microarray experiments still is a field of extensive investigation. Although new approaches and ...
104
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BMCBI
2008
15 years 17 days ago
2008
Background: Hierarchical clustering is a widely applied tool in the analysis of microarray gene expression data. The assessment of cluster stability is a major challenge in cluste...
BMCBI
2007
2007
FUNC: a package for detecting significant associations between gene sets and ontological annotations
15 years 17 days ago
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...