Sciweavers

2274 search results - page 434 / 455
» A Tale of Two Projects
Sort
View
101
Voted
BMCBI
2010
90views more  BMCBI 2010»
15 years 3 months ago
Using caching and optimization techniques to improve performance of the Ensembl website
Background: The Ensembl web site has provided access to genomic information for almost 10 years. During this time the amount of data available through Ensembl has grown dramatical...
Anne Parker, Eugene Bragin, Simon Brent, Bethan Pr...
117
Voted
BMCBI
2010
169views more  BMCBI 2010»
15 years 3 months ago
eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics
Background: Mitochondrial DNA (mtDNA) is widely being used for population genetics, forensic DNA fingerprinting and clinical disease association studies. The recent past has uncov...
Hansi Weißensteiner, Sebastian Schönher...
BMCBI
2010
189views more  BMCBI 2010»
15 years 3 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...
127
Voted
BMCBI
2010
154views more  BMCBI 2010»
15 years 3 months ago
An algorithm for automated closure during assembly
Background: Finishing is the process of improving the quality and utility of draft genome sequences generated by shotgun sequencing and computational assembly. Finishing can invol...
Sergey Koren, Jason R. Miller, Brian Walenz, Grang...
BMCBI
2008
106views more  BMCBI 2008»
15 years 3 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...