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BMCBI
2008
97views more  BMCBI 2008»
15 years 2 months ago
SiteSeek: Post-translational modification analysis using adaptive locality-effective kernel methods and new profiles
Background: Post-translational modifications have a substantial influence on the structure and functions of protein. Post-translational phosphorylation is one of the most common m...
Paul D. Yoo, Yung Shwen Ho, Bing Bing Zhou, Albert...
BMCBI
2008
132views more  BMCBI 2008»
15 years 2 months ago
Clustering ionic flow blockade toggles with a Mixture of HMMs
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties with potential implications f...
Alexander G. Churbanov, Stephen Winters-Hilt
EXPERT
2008
120views more  EXPERT 2008»
15 years 2 months ago
The CKC Challenge: Exploring Tools for Collaborative Knowledge Construction
The great success of Web 2.0 is mainly fuelled by an infrastructure that allows web users to create, share, tag, and connect content and knowledge easily. The tools for developing...
Natalya Fridman Noy, Abhita Chugh, Harith Alani
BMCBI
2006
239views more  BMCBI 2006»
15 years 2 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
137views more  BMCBI 2006»
15 years 2 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...