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» A Theory of Expressiveness in Mechanisms
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BMCBI
2005
133views more  BMCBI 2005»
14 years 10 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
TAPOS
1998
93views more  TAPOS 1998»
14 years 9 months ago
Object Acquaintance Selection and Binding
Large object-oriented systems have, at least, four characteristics that complicate object communication, i.e the system is distributed and contains large numbers, e.g. thousands, ...
Jan Bosch
BMCBI
2011
14 years 5 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
BMCBI
2011
14 years 1 months ago
PRIN, a predicted rice interactome network
Background: Protein-protein interactions play a fundamental role in elucidating the molecular mechanisms of biomolecular function, signal transductions and metabolic pathways of l...
Haibin Gu, Pengcheng Zhu, Yinming Jiao, Yijun Meng...
JAMIA
2011
94views more  JAMIA 2011»
14 years 26 days ago
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...