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» A Theory of Expressiveness in Mechanisms
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BMCBI
2010
139views more  BMCBI 2010»
14 years 10 months ago
RNAstructure: software for RNA secondary structure prediction and analysis
Background: To understand an RNA sequence's mechanism of action, the structure must be known. Furthermore, target RNA structure is an important consideration in the design of...
Jessica S. Reuter, David H. Mathews
BMCBI
2008
148views more  BMCBI 2008»
14 years 10 months ago
Automating dChip: toward reproducible sharing of microarray data analysis
Background: During the past decade, many software packages have been developed for analysis and visualization of various types of microarrays. We have developed and maintained the...
Cheng Li
BMCBI
2008
105views more  BMCBI 2008»
14 years 10 months ago
Improving the prediction of mRNA extremities in the parasitic protozoan Leishmania
Background: Leishmania and other members of the Trypanosomatidae family diverged early on in eukaryotic evolution and consequently display unique cellular properties. Their appare...
Martin Smith, Mathieu Blanchette, Barbara Papadopo...
BMCBI
2006
110views more  BMCBI 2006»
14 years 10 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
JFP
2008
72views more  JFP 2008»
14 years 10 months ago
Dynamic rebinding for marshalling and update, via redex-time and destruct-time reduction
Most programming languages adopt static binding, but for distributed programming an exclusive reliance on static binding is too restrictive: dynamic binding is required in various...
Peter Sewell, Gareth Stoyle, Michael Hicks, Gavin ...