Background: The unsupervised discovery of structures (i.e. clusterings) underlying data is a central issue in several branches of bioinformatics. Methods based on the concept of s...
Non-negative matrix factorization (NMF) has become a standard tool in data mining, information retrieval, and signal processing. It is used to factorize a non-negative data matrix ...
C. Thurau, K. Kersting, M. Wahabzada, and C. Bauck...
Problems involving high-dimensional data, such as pattern recognition, image analysis, and gene clustering, often require a preliminary step of dimension reduction before or durin...
Background: MicroRNAs (miRs) are small noncoding RNAs that bind to complementary/partially complementary sites in the 3' untranslated regions of target genes to regulate prot...
Jishou Ruan, Hanzhe Chen, Lukasz A. Kurgan, Ke Che...
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...