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» A Transcriptional Approach to Gene Clustering
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CEC
2011
IEEE
13 years 9 months ago
Inferring transcriptional regulators for sets of co-expressed genes by multi-objective evolutionary optimization
Abstract—Higher organisms are able to respond to continuously changing external conditions by transducing cellular signals into specific regulatory programs, which control gene ...
Adrian Schröder, Clemens Wrzodek, Johannes Wo...
RECOMB
2008
Springer
15 years 10 months ago
Computation of Median Gene Clusters
Whole genome comparison based on gene order has become a popular approach in comparative genomics. An important task in this field is the detection of gene clusters, i.e. sets of g...
Sebastian Böcker, Katharina Jahn, Julia Mixta...
GCB
2005
Springer
98views Biometrics» more  GCB 2005»
15 years 3 months ago
Composite Module Analyst: A Fitness-Based Tool for Prediction of Transcription Regulation
: Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely...
Alexander E. Kel, Tatiana Konovalova, Tagir Valeev...
BMCBI
2008
98views more  BMCBI 2008»
14 years 10 months ago
GBNet: Deciphering regulatory rules in the co-regulated genes using a Gibbs sampler enhanced Bayesian network approach
Background: Combinatorial regulation of transcription factors (TFs) is important in determining the complex gene expression patterns particularly in higher organisms. Deciphering ...
Li Shen, Jie Liu, Wei Wang
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
An improved distance measure between the expression profiles linking co-expression and co-regulation in mouse
Background: Many statistical algorithms combine microarray expression data and genome sequence data to identify transcription factor binding motifs in the low eukaryotic genomes. ...
Ryung S. Kim, Hongkai Ji, Wing Hung Wong