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» A Transcriptional Approach to Gene Clustering
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CCE
2008
14 years 10 months ago
Identification of regulatory mechanisms of the hepatic response to thermal injury
The purpose of this paper is to evaluate the hypothesis that a systems biology approach can be developed such that a set of transcription factors, relevant to burn-induced inflamm...
Eric Yang, Timothy Maguire, Martin L. Yarmush, Fra...
IJDMB
2008
117views more  IJDMB 2008»
14 years 9 months ago
Scoring and summarising gene product clusters using the Gene Ontology
: We propose an approach for quantifying the biological relatedness between gene products, based on their properties, and measure their similarities using exclusively statistical N...
Spiridon C. Denaxas, Christos Tjortjis
BMCBI
2010
115views more  BMCBI 2010»
14 years 10 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
WILF
2007
Springer
147views Fuzzy Logic» more  WILF 2007»
15 years 3 months ago
Fuzzy Ensemble Clustering for DNA Microarray Data Analysis
Two major problems related the unsupervised analysis of gene expression data are represented by the accuracy and reliability of the discovered clusters, and by the biological fact ...
Roberto Avogadri, Giorgio Valentini
BMCBI
2008
134views more  BMCBI 2008»
14 years 10 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane