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» A Transcriptional Approach to Gene Clustering
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BMCBI
2008
116views more  BMCBI 2008»
14 years 10 months ago
The combination approach of SVM and ECOC for powerful identification and classification of transcription factor
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
Guangyong Zheng, Ziliang Qian, Qing Yang, Chaochun...
BMCBI
2006
106views more  BMCBI 2006»
14 years 9 months ago
GONOME: measuring correlations between GO terms and genomic positions
Background:Current methods to find significantly under- and over-represented gene ontology (GO) terms in a set of genes consider the genes as equally probable "balls in a bag...
Stefan M. Stanley, Timothy L. Bailey, John S. Matt...
BMCBI
2006
82views more  BMCBI 2006»
14 years 9 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
TCSB
2010
14 years 8 months ago
Rule-Based Modeling of Transcriptional Attenuation at the Tryptophan Operon
Transcriptional attenuation at E.coli’s tryptophan operon is a prime example of RNA-mediated gene regulation. In this paper, we present a discrete stochastic model for this pheno...
Céline Kuttler, Cédric Lhoussaine, M...
BMCBI
2008
118views more  BMCBI 2008»
14 years 10 months ago
Inferring transcriptional compensation interactions in yeast via stepwise structure equation modeling
Background: With the abundant information produced by microarray technology, various approaches have been proposed to infer transcriptional regulatory networks. However, few appro...
Grace S. Shieh, Chung-Ming Chen, Ching-Yun Yu, Jui...