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» A Transcriptional Approach to Gene Clustering
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BMCBI
2005
94views more  BMCBI 2005»
14 years 9 months ago
Measuring similarities between transcription factor binding sites
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
CSB
2005
IEEE
125views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Discriminative Discovery of Transcription Factor Binding Sites from Location Data
Motivation: The availability of genome-wide location analyses based on chromatin immunoprecipitation (ChIP) data gives a new insight for in silico analysis of transcriptional regu...
Yuji Kawada, Yasubumi Sakakibara
ICASSP
2011
IEEE
14 years 1 months ago
Biological pathway inference using manifold embedding
Disease occurs due to aberrant modulation of biological pathways. Identification of activated gene pathways from gene expression data is an important problem. In this work, we de...
Arvind Rao, Alfred O. Hero
TCSB
2008
14 years 9 months ago
Clustering Time-Series Gene Expression Data with Unequal Time Intervals
Clustering gene expression data given in terms of time-series is a challenging problem that imposes its own particular constraints, namely exchanging two or more time points is not...
Luis Rueda, Ataul Bari, Alioune Ngom
BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian