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BIBE
2007
IEEE
127views Bioinformatics» more  BIBE 2007»
15 years 1 months ago
Gene Selection via Matrix Factorization
The recent development of microarray gene expression techniques have made it possible to offer phenotype classification of many diseases. However, in gene expression data analysis...
Fei Wang, Tao Li
BMCBI
2008
128views more  BMCBI 2008»
14 years 9 months ago
In silico analysis of expressed sequence tags from Trichostrongylus vitrinus (Nematoda): comparison of the automated ESTExplorer
Background: The analysis of expressed sequence tags (EST) offers a rapid and cost effective approach to elucidate the transcriptome of an organism, but requires several computatio...
Shivashankar H. Nagaraj, Robin B. Gasser, Alasdair...
ICASSP
2011
IEEE
14 years 1 months ago
A mutual information based approach for evaluating the quality of clustering
In this paper, a new method for evaluating the quality of clustering of genes is proposed based on mutual information criterion. Instead of using the conventional histogram-based ...
Shaikh Anowarul Fattah, Chia-Chun Lin, Sun-Yuan Ku...
BMCBI
2006
165views more  BMCBI 2006»
14 years 10 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2006
131views more  BMCBI 2006»
14 years 10 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller