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» A Transcriptional Approach to Gene Clustering
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BMCBI
2007
130views more  BMCBI 2007»
14 years 10 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BMCBI
2007
97views more  BMCBI 2007»
14 years 10 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
BMCBI
2008
145views more  BMCBI 2008»
14 years 10 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
DIS
2004
Springer
15 years 3 months ago
A Methodology for Biologically Relevant Pattern Discovery from Gene Expression Data
Abstract. One of the most exciting scientific challenges in functional genomics concerns the discovery of biologically relevant patterns from gene expression data. For instance, i...
Ruggero G. Pensa, Jérémy Besson, Jea...
PR
2008
88views more  PR 2008»
14 years 9 months ago
Modified global k
Clustering in gene expression data sets is a challenging problem. Different algorithms for clustering of genes have been proposed. However due to the large number of genes only a ...
Adil M. Bagirov