Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Abstract- In this paper we address the problem of finding valid solutions for the problem of inferring gene regulatory networks. Different approaches to directly infer the depende...
Christian Spieth, Felix Streichert, Nora Speer, An...
Discovering coherent gene expression patterns in time-series gene expression data is an important task in bioinformatics research and biomedical applications. In this paper, we pr...
The genetical genomics approach has been used to study the genetic basis of variation in gene expression, where putative transcriptional regulators of genes are identified via gene...
Background: The analysis of the promoter sequence of genes with similar expression patterns is a basic tool to annotate common regulatory elements. Multiple sequence alignments ar...