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» A Transcriptional Approach to Gene Clustering
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BMCBI
2005
79views more  BMCBI 2005»
14 years 9 months ago
Mathematical design of prokaryotic clone-based microarrays
Background: Clone-based microarrays, on which each spot represents a random genomic fragment, are a good alternative to open reading frame-based microarrays, especially for microo...
Bart Pieterse, Elisabeth J. Quirijns, Frank H. J. ...
BMCBI
2008
148views more  BMCBI 2008»
14 years 10 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
BMCBI
2007
147views more  BMCBI 2007»
14 years 10 months ago
Statistical analysis and significance testing of serial analysis of gene expression data using a Poisson mixture model
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...
Scott D. Zuyderduyn
BMCBI
2004
133views more  BMCBI 2004»
14 years 9 months ago
Artificial neural network approach for selection of susceptible single nucleotide polymorphisms and construction of prediction m
Background: Screening of various gene markers such as single nucleotide polymorphism (SNP) and correlation between these markers and development of multifactorial disease have pre...
Yasuyuki Tomita, Shuta Tomida, Yuko Hasegawa, Yoic...
BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...