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» A Transcriptional Approach to Gene Clustering
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BMCBI
2010
113views more  BMCBI 2010»
14 years 10 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
ICARIS
2004
Springer
15 years 3 months ago
Definition of MHC Supertypes Through Clustering of MHC Peptide Binding Repertoires
MHC molecules, also known in the human as human leukocyte antigens (HLA), display peptides on antigen presenting cell surfaces for subsequent T cell recognition. Identification of ...
Pedro A. Reche, Ellis L. Reinherz
EVOW
2006
Springer
15 years 1 months ago
Hierarchical Clustering, Languages and Cancer
In this paper, we introduce a novel objective function for the hierarchical clustering of data from distance matrices, a very relevant task in Bioinformatics. To test the robustnes...
Pritha Mahata, Wagner Costa, Carlos Cotta, Pablo M...
BMCBI
2006
158views more  BMCBI 2006»
14 years 9 months ago
Parallelization of multicategory support vector machines (PMC-SVM) for classifying microarray data
Background: Multicategory Support Vector Machines (MC-SVM) are powerful classification systems with excellent performance in a variety of data classification problems. Since the p...
Chaoyang Zhang, Peng Li, Arun Rajendran, Youping D...
BMCBI
2007
125views more  BMCBI 2007»
14 years 9 months ago
Identification of discriminative characteristics for clusters from biologic data with InforBIO software
Background: There are a number of different methods for generation of trees and algorithms for phylogenetic analysis in the study of bacterial taxonomy. Genotypic information, suc...
Naoto Tanaka, Masataka Uchino, Satoru Miyazaki, Hi...