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» A Transcriptional Approach to Gene Clustering
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BMCBI
2005
106views more  BMCBI 2005»
14 years 9 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
14 years 10 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
RECOMB
2010
Springer
14 years 8 months ago
Consistency of Sequence-Based Gene Clusters
In comparative genomics, various combinatorial models can be used to specify gene clusters — groups of genes that are co-located in a set of genomes. Several approaches have been...
Roland Wittler, Jens Stoye
BMCBI
2007
149views more  BMCBI 2007»
14 years 9 months ago
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
BMCBI
2010
167views more  BMCBI 2010»
14 years 10 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...