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BMCBI
2007
134views more  BMCBI 2007»
14 years 10 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
BMCBI
2010
127views more  BMCBI 2010»
14 years 10 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
BMCBI
2006
101views more  BMCBI 2006»
14 years 10 months ago
Predicting residue contacts using pragmatic correlated mutations method: reducing the false positives
Background: Predicting residues' contacts using primary amino acid sequence alone is an important task that can guide 3D structure modeling and can verify the quality of the ...
Petras J. Kundrotas, Emil Alexov
NIPS
2004
14 years 11 months ago
Large-Scale Prediction of Disulphide Bond Connectivity
The formation of disulphide bridges among cysteines is an important feature of protein structures. Here we develop new methods for the prediction of disulphide bond connectivity. ...
Pierre Baldi, Jianlin Cheng, Alessandro Vullo
BMCBI
2010
179views more  BMCBI 2010»
14 years 10 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...